AHCYL2

Across TCGA patient cohorts, AHCYL2 mutation is significantly associated with the RNA expression of many other genes, with 1,813 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AHCYL2-associated genes across cancer lineages are TUBGCP4, MRTO4, and UBE2T. Each is linked with AHCYL2 in more than 2 cancer types. Because this analysis shows association rather than direction, both AHCYL2-to-partner and partner-to-AHCYL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TUBGCP4 grouped by AHCYL2-low versus AHCYL2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AHCYL2→partner) and Y-score (partner→AHCYL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TUBGCP4 →	+0.605	+3.691	<.001	.001	3	3
UCEC	MRTO4 →	+0.463	+2.392	<.001	<.001	3	3
UCEC	UBE2T →	+0.544	+3.470	.007	.002	3	3
UCEC	UBE2L3 →	+0.380	+3.774	<.001	<.001	3	3
CESC	MIR4510 →	+0.300	+5.342	<.001	.002	3	2
HNSC	KRTAP19-5 →	+0.532	+4.260	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,813 associations by consensus.

TUBGCP4 by AHCYL2 expression — UCEC

Explore this box plot interactively →