AHCYL2

Across TCGA cell cohorts, AHCYL2 protein abundance is significantly associated with the go_rna of many other GO terms, with 1,013 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AHCYL2-associated GO terms across cancer lineages are Muscle cell migration, Regulation of activin receptor signaling pathway, and Intrinsic apoptotic signaling pathway in response to oxidative stress. Each is linked with AHCYL2 in more than 2 cancer types. Because this analysis shows association rather than direction, both AHCYL2-to-partner and partner-to-AHCYL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Muscle cell migration grouped by AHCYL2-low versus AHCYL2-high in LUNG_NSCLC_LUAD.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AHCYL2→partner) and Y-score (partner→AHCYL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Muscle cell migration →	+0.246	+2.510	.009	.002	3	3
BLOOD_Leukemia	Regulation of activin receptor signaling pathway →	-0.068	-1.762	.005	.006	3	3
BREAST	Intrinsic apoptotic signaling pathway in response to oxidative stress →	+0.172	+2.211	.004	.006	3	2
SKIN	Negative regulation of lipid storage →	+0.095	+1.406	.008	.001	2	3
SKIN	Disruption of anatomical structure in another organism →	+0.111	+1.301	.002	.001	3	2
SKIN	Response to bile acid →	+0.124	+1.223	.004	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,013 associations by consensus.

Muscle cell migration by AHCYL2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →