AHCYL2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, AHCYL2 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AHCYL2-associated genes across cancer lineages are SMIM23. Each is linked with AHCYL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both AHCYL2-to-partner and partner-to-AHCYL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMIM23 grouped by AHCYL2-low versus AHCYL2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AHCYL2→partner) and Y-score (partner→AHCYL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaSMIM23 →+0.022+5.569<.001.00131
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

SMIM23 by AHCYL2 expression — BLOOD_Leukemia

Box plot of SMIM23 in AHCYL2-low vs AHCYL2-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration