AHCY

Across TCGA patient cohorts, AHCY RNA expression is significantly associated with the protein abundance of many other proteins, with 18,775 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AHCY-associated proteins across cancer lineages are UTP4, PUS7, and MPHOSPH10. Each is linked with AHCY in more than 7 cancer types. Because this analysis shows association rather than direction, both AHCY-to-partner and partner-to-AHCY results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AHCY versus UTP4 in LSCC, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AHCY→partner) and Y-score (partner→AHCY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UTP4 →	+0.338	+0.798	<.001	<.001	3	8
LSCC	PUS7 →	+0.524	+0.813	<.001	<.001	3	8
LSCC	MPHOSPH10 →	+0.416	+0.865	<.001	<.001	3	8
BRCA	WDR43 →	+0.372	+0.589	<.001	<.001	3	8
LSCC	BOP1 →	+0.356	+0.887	<.001	<.001	3	8
LSCC	DDX52 →	+0.435	+0.723	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,775 associations by consensus.

AHCY vs UTP4 — LSCC

Explore this scatter interactively →