AHCTF1

Across TCGA pan-cancer cohorts, AHCTF1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated AHCTF1 data layer compared with 29 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher AHCTF1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated AHCTF1 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

HNSC, PDAC, and CCRCC are the cancer types where AHCTF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.741	0.946	<.001	98	view →
PDAC	OS	Tertile	II,III,IV	0.361	0.706	.002	24	view →
CCRCC	DFS	Tertile	III,IV	0.544	0.861	.018	13	view →
LUAD	DFS	Quartile	III,IV	0.784	0.337	.026	9	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

AHCTF1–HNSC (OS)

Open the HNSC breakdown →