AHCTF1

Across TCGA cell cohorts, AHCTF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,298 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible AHCTF1-associated GO terms across cancer lineages are Nuclear pore organization, Nuclear pore complex assembly, and Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery. Each is linked with AHCTF1 in more than 19 cancer types. Because this analysis shows association rather than direction, both AHCTF1-to-partner and partner-to-AHCTF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear pore organization grouped by AHCTF1-low versus AHCTF1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AHCTF1→partner) and Y-score (partner→AHCTF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nuclear pore organization →	+0.153	+0.696	<.001	<.001	3	20
BREAST	Nuclear pore complex assembly →	+0.141	+1.101	<.001	<.001	3	19
BONE	Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery →	+0.190	+1.069	<.001	<.001	3	18
SOFT_TISSUE	Positive regulation of mRNA processing →	+0.138	+0.893	<.001	<.001	3	17
BONE	Transcription by RNA polymerase I →	+0.104	+0.716	<.001	.001	3	17
BLOOD_Myeloma	Regulation of sister chromatid cohesion →	+0.114	+1.173	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,298 associations by consensus.

Nuclear pore organization by AHCTF1 expression — BONE

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