AGXT2

Across TCGA patient cohorts, AGXT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,081 significant associations in total. STAD shows the largest number of these associations.

The most reproducible AGXT2-associated GO terms across cancer lineages are Multicellular organism growth, Amine metabolic process, and Pyruvate family amino acid metabolic process. Each is linked with AGXT2 in more than 10 cancer types. Because this analysis shows association rather than direction, both AGXT2-to-partner and partner-to-AGXT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Multicellular organism growth grouped by AGXT2-low versus AGXT2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AGXT2→partner) and Y-score (partner→AGXT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Multicellular organism growth →	+0.055	+0.163	<.001	<.001	3	11
STAD	Amine metabolic process →	+0.036	+0.160	<.001	<.001	3	11
TGCT	Pyruvate family amino acid metabolic process →	-0.137	-0.418	<.001	<.001	3	10
ESCA	Protein stabilization →	+0.076	+0.252	<.001	<.001	3	10
ESCA	Establishment of protein localization to chromosome →	+0.071	+0.168	<.001	.004	3	10
ESCA	Negative regulation of TORC1 signaling →	+0.072	+0.200	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,081 associations by consensus.

Multicellular organism growth by AGXT2 expression — STAD

Explore this box plot interactively →