AGXT

Across TCGA patient cohorts, AGXT RNA expression is significantly associated with the go_rna of many other GO terms, with 6,958 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible AGXT-associated GO terms across cancer lineages are Isoprenoid transport, Pyruvate family amino acid metabolic process, and L-cysteine metabolic process. Each is linked with AGXT in more than 11 cancer types. Because this analysis shows association rather than direction, both AGXT-to-partner and partner-to-AGXT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Isoprenoid transport grouped by AGXT-low versus AGXT-high in KIRC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AGXT→partner) and Y-score (partner→AGXT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	Isoprenoid transport →	+0.075	+0.314	<.001	<.001	3	12
TGCT	Pyruvate family amino acid metabolic process →	-0.129	-0.255	<.001	<.001	3	12
LAML	L-cysteine metabolic process →	-0.163	-0.701	<.001	<.001	3	11
TGCT	Glycine biosynthetic process →	-0.064	-0.287	<.001	.001	3	11
ESCA	Nucleoside bisphosphate biosynthetic process →	+0.077	+0.445	<.001	<.001	3	11
ESCA	Regulation of carbohydrate metabolic process →	+0.062	+0.478	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,958 associations by consensus.

Isoprenoid transport by AGXT expression — KIRC

Explore this box plot interactively →