AGRP

Across TCGA pan-cancer cohorts, AGRP Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated AGRP data layer compared with 21 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher AGRP Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated AGRP expression acts as an unfavorable survival marker.

LIHC are the cancer types where AGRP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Median	All	0.096	0.543	.028	6	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

AGRP–LIHC (DFS)

Open the LIHC breakdown →