Across TCGA patient cohorts, AGRN RNA expression is significantly associated with the RNA expression of many other genes, with 18,836 significant associations in total. KIRP shows the largest number of these associations.

The most reproducible AGRN-associated genes across cancer lineages are SDF4, PLXNB2, and ARHGEF17. Each is linked with AGRN in more than 32 cancer types. Because this analysis shows association rather than direction, both AGRN-to-partner and partner-to-AGRN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGRN→partner) and Y-score (partner→AGRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	SDF4 →	+0.820	+1.990	<.001	<.001	3	33
THYM	PLXNB2 →	+1.833	+1.939	<.001	<.001	3	32
THYM	ARHGEF17 →	+1.623	+1.821	<.001	<.001	3	32
ACC	PCNX3 →	+1.245	+1.452	<.001	<.001	3	31
SCLC	TNRC18 →	+1.226	+1.682	<.001	<.001	3	31
TGCT	COL18A1 →	+2.401	+2.171	<.001	<.001	3	31

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,836 associations by consensus.

Exploration

AGRN survival (RNA) · tumor vs normal (RNA) · all AGRN data types