Across TCGA cell cohorts, AGRN RNA expression is significantly associated with the go_rna of many other GO terms, with 5,141 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible AGRN-associated GO terms across cancer lineages are Positive regulation of neuromuscular junction development, Epithelial cell development, and Glial cell migration. Each is linked with AGRN in more than 17 cancer types. Because this analysis shows association rather than direction, both AGRN-to-partner and partner-to-AGRN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AGRN→partner) and Y-score (partner→AGRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of neuromuscular junction development →	+0.368	+2.256	<.001	<.001	3	18
PANCREAS	Epithelial cell development →	+0.097	+1.130	<.001	.003	3	17
OESOPHAGUS	Glial cell migration →	+0.188	+2.331	.003	.002	3	16
URINARY_TRACT	Positive regulation of intracellular protein transport →	+0.076	+1.648	.006	.001	3	16
UPPER_AERODIGESTIVE_TRACT	Regulation of pattern recognition receptor signaling pathway →	+0.083	+1.986	<.001	<.001	3	16
STOMACH	Regulation of cell junction assembly →	+0.062	+1.655	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,141 associations by consensus.

Exploration

AGRN survival (RNA) · tumor vs normal (RNA) · all AGRN data types