AGR3

Across TCGA patient cohorts, AGR3 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,942 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AGR3-associated proteins across cancer lineages are SGSM3, MLPH, and AGR2. Each is linked with AGR3 in more than 7 cancer types. Because this analysis shows association rather than direction, both AGR3-to-partner and partner-to-AGR3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AGR3 versus SGSM3 in BRCA, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AGR3→partner) and Y-score (partner→AGR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SGSM3 →	+0.421	+3.089	<.001	<.001	3	8
BRCA	MLPH →	+1.106	+4.266	<.001	<.001	3	7
BRCA	AGR2 →	+1.541	+3.880	<.001	<.001	3	7
LUAD	MLPH_S337 →	+1.406	+1.580	<.001	<.001	3	6
BRCA	NOSTRIN →	+0.985	+3.613	<.001	<.001	3	6
COAD	PDXDC1 →	+0.493	+2.420	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,942 associations by consensus.

AGR3 vs SGSM3 — BRCA

Explore this scatter interactively →