AGR2

Across TCGA patient cohorts, AGR2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,517 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible AGR2-associated proteins across cancer lineages are AGR3, PDXDC1, and BCAS1. Each is linked with AGR2 in more than 7 cancer types. Because this analysis shows association rather than direction, both AGR2-to-partner and partner-to-AGR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AGR2 versus AGR3 in BRCA, with a Pearson correlation of 0.71.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AGR2→partner) and Y-score (partner→AGR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AGR3 →	+1.381	+4.426	<.001	<.001	3	8
COAD	PDXDC1 →	+0.452	+1.694	<.001	<.001	3	7
LUAD	BCAS1 →	+1.680	+2.101	<.001	<.001	3	7
BRCA	GALNT7 →	+0.702	+3.402	<.001	<.001	3	7
BRCA	GOLM1 →	+0.797	+3.137	<.001	<.001	3	7
BRCA	TFF3 →	+1.579	+2.983	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,517 associations by consensus.

AGR2 vs AGR3 — BRCA

Explore this scatter interactively →