AGR2

Across TCGA patient cohorts, AGR2 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible AGR2-associated genes across cancer lineages are mv Endothelial cells and Sebocytes. Each is linked with AGR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both AGR2-to-partner and partner-to-AGR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mv Endothelial cells grouped by AGR2-low versus AGR2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGR2→partner) and Y-score (partner→AGR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	mv Endothelial cells →	-0.031	-2.993	.044	.037	2	1
UCEC	Sebocytes →	-0.033	-2.437	.006	.020	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

mv Endothelial cells by AGR2 expression — SKCM

Explore this box plot interactively →