AGPAT5P1

Across TCGA pan-cancer cohorts, AGPAT5P1 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated AGPAT5P1 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher AGPAT5P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated AGPAT5P1 expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

BLCA, LIHC, and UCEC are the cancer types where AGPAT5P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	III,IV	0.105	0.575	<.001	54	view →
LIHC	DFS	Tertile	All	0.045	0.553	<.001	54	view →
UCEC	OS	Tertile	All	0.580	0.928	.001	36	view →
KIRP	OS	Tertile	All	0.191	0.699	<.001	27	view →
ESCA	OS	Tertile	III,IV	1.000	0.380	.030	12	view →
LUSC	OS	Tertile	All	0.362	0.727	.034	12	view →
GBM	DFS	Tertile	All	0.073	0.250	.002	9	view →
COAD	OS	Tertile	II,III,IV	0.481	0.788	.036	9	view →
LGG	OS	Tertile	All	0.644	0.889	.023	6	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

AGPAT5P1–BLCA (DFS)

Open the BLCA breakdown →