AGPAT5

Across TCGA patient cohorts, AGPAT5 mutation is significantly associated with the RNA expression of many other genes, with 2,406 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AGPAT5-associated genes across cancer lineages are RNA5SP534, BPY2DP, and MTDHP1. Each is linked with AGPAT5 in more than 1 cancer types. Because this analysis shows association rather than direction, both AGPAT5-to-partner and partner-to-AGPAT5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP534 grouped by AGPAT5-low versus AGPAT5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGPAT5→partner) and Y-score (partner→AGPAT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP534 →	+0.221	+2.171	<.001	.006	3	2
SKCM	BPY2DP →	+0.164	+7.816	<.001	.008	3	2
UCEC	MTDHP1 →	-0.226	-2.875	.007	.001	3	1
UCEC	TMCC1-AS1 →	-0.306	-1.651	.005	.008	3	1
UCEC	CCL5 →	+0.935	+2.923	.002	<.001	3	1
UCEC	BBIP1P1 →	+0.313	+2.052	.005	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,406 associations by consensus.

RNA5SP534 by AGPAT5 expression — UCEC

Explore this box plot interactively →