AGPAT5

Across TCGA cell cohorts, AGPAT5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,972 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible AGPAT5-associated GO terms across cancer lineages are Regulation of regulatory ncRNA-mediated heterochromatin formation, Negative regulation of regulatory ncRNA-mediated heterochromatin formation, and snRNA 3'-end processing. Each is linked with AGPAT5 in more than 16 cancer types. Because this analysis shows association rather than direction, both AGPAT5-to-partner and partner-to-AGPAT5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of regulatory ncRNA-mediated heterochromatin formation grouped by AGPAT5-low versus AGPAT5-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AGPAT5→partner) and Y-score (partner→AGPAT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of regulatory ncRNA-mediated heterochromatin formation →	+0.161	+1.193	<.001	<.001	3	17
STOMACH	Negative regulation of regulatory ncRNA-mediated heterochromatin formation →	+0.161	+1.193	<.001	<.001	3	17
BONE	snRNA 3'-end processing →	+0.103	+1.294	<.001	<.001	3	14
STOMACH	Negative regulation of sister chromatid cohesion →	+0.144	+1.239	.004	.001	3	14
UPPER_AERODIGESTIVE_TRACT	DNA-templated transcription initiation →	+0.072	+0.967	<.001	.002	3	14
SOFT_TISSUE	Regulation of DNA replication →	+0.084	+1.047	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,972 associations by consensus.

Regulation of regulatory ncRNA-mediated heterochromatin formation by AGPAT5 expression — STOMACH

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