Across TCGA patient cohorts, AGPAT1 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AGPAT1-associated genes across cancer lineages are MEK1, 14-3-3_beta, and ER-alpha. Each is linked with AGPAT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AGPAT1-to-partner and partner-to-AGPAT1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGPAT1→partner) and Y-score (partner→AGPAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.534	+3.169	.005	.019	3	2
UCEC	14-3-3_beta →	-0.128	-2.973	.014	.035	3	1
UCEC	ER-alpha →	-0.913	-3.321	.034	.010	3	1
UCEC	GATA6 →	-0.197	-2.992	.027	.036	3	1
UCEC	JNK_pT183_Y185 →	-0.215	-3.308	.014	.010	3	1
UCEC	Ku80 →	+0.316	+2.183	.010	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

AGPAT1 survival (RNA) · tumor vs normal (RNA) · all AGPAT1 data types