Across TCGA patient cohorts, AGMO mutation is significantly associated with the RNA expression of many other genes, with 3,702 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AGMO-associated genes across cancer lineages are COX4I2, LMO2, and S100B. Each is linked with AGMO in more than 2 cancer types. Because this analysis shows association rather than direction, both AGMO-to-partner and partner-to-AGMO results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGMO→partner) and Y-score (partner→AGMO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	COX4I2 →	-0.605	-1.902	.004	.005	3	3
UCEC	LMO2 →	-0.698	-1.689	<.001	.002	3	3
LUAD	S100B →	-1.232	-3.584	<.001	.002	3	3
LUAD	MIR4445 →	+0.147	+2.777	.001	.009	3	3
BLCA	RNU6-19P →	+0.470	+4.216	.002	.001	3	3
UCEC	ERG →	-0.455	-2.129	.002	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,702 associations by consensus.

Exploration

AGMO survival (RNA) · tumor vs normal (RNA) · all AGMO data types