Across TCGA patient cohorts, AGMO mutation is significantly associated with the total protein of many other genes, with 67 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AGMO-associated genes across cancer lineages are ASNS, TIGAR, and FoxM1. Each is linked with AGMO in more than 2 cancer types. Because this analysis shows association rather than direction, both AGMO-to-partner and partner-to-AGMO results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGMO→partner) and Y-score (partner→AGMO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ASNS →	+0.488	+3.584	.011	.002	3	3
UCEC	TIGAR →	+0.124	+1.348	.014	.018	3	3
LUAD	FoxM1 →	+0.324	+3.472	.002	.002	3	2
LUAD	PCNA →	+0.306	+2.459	<.001	.017	3	2
UCEC	4E-BP1 →	+0.349	+3.837	<.001	<.001	3	2
UCEC	A-Raf_pS299 →	-0.112	-1.678	.004	.021	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 67 associations by consensus.

Exploration

AGMO survival (RNA) · tumor vs normal (RNA) · all AGMO data types