Across TCGA cell cohorts, AGMO mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible AGMO-associated genes across cancer lineages are CCL18, OR4P4, and GPR26. Each is linked with AGMO in more than 1 cancer types. Because this analysis shows association rather than direction, both AGMO-to-partner and partner-to-AGMO results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGMO→partner) and Y-score (partner→AGMO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	CCL18 →	+0.040	+4.643	<.001	.008	3	2
STOMACH	OR4P4 →	+0.012	+4.285	<.001	.007	3	1
BLOOD_Leukemia	GPR26 →	+0.077	+5.539	<.001	.003	3	1
BLOOD_Leukemia	SCGB3A2 →	+0.144	+4.922	<.001	.009	3	1
BLOOD_Leukemia	OR10Q1 →	+0.032	+5.969	<.001	.001	3	1
BLOOD_Leukemia	LRRC55 →	+0.006	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

AGMO survival (RNA) · tumor vs normal (RNA) · all AGMO data types