AGMAT

Across TCGA patient cohorts, AGMAT protein abundance is significantly associated with the RNA expression of many other genes, with 11,409 significant associations in total. COAD shows the largest number of these associations.

The most reproducible AGMAT-associated genes across cancer lineages are SPARC, FRMD6, and CERCAM. Each is linked with AGMAT in more than 4 cancer types. Because this analysis shows association rather than direction, both AGMAT-to-partner and partner-to-AGMAT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AGMAT versus SPARC in BRCA, with a Pearson correlation of -0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGMAT→partner) and Y-score (partner→AGMAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SPARC →	-1.121	-0.510	.001	.006	3	5
PDAC	FRMD6 →	-1.039	-1.287	<.001	<.001	3	4
BRCA	CERCAM →	-0.853	-0.507	.001	<.001	3	4
BRCA	RAB31 →	-1.057	-0.517	.003	.006	3	4
COAD	RNF144A →	-0.737	-0.569	<.001	<.001	3	4
PDAC	CLIC4 →	-0.657	-0.989	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,409 associations by consensus.

AGMAT vs SPARC — BRCA

Explore this scatter interactively →