AGMAT

Across TCGA cell cohorts, AGMAT RNA expression is significantly associated with the go_rna of many other GO terms, with 3,687 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AGMAT-associated GO terms across cancer lineages are Putrescine biosynthetic process from arginine, Putrescine biosynthetic process, and Putrescine metabolic process. Each is linked with AGMAT in more than 15 cancer types. Because this analysis shows association rather than direction, both AGMAT-to-partner and partner-to-AGMAT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Putrescine biosynthetic process from arginine grouped by AGMAT-low versus AGMAT-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AGMAT→partner) and Y-score (partner→AGMAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Putrescine biosynthetic process from arginine →	-0.261	-0.886	<.001	<.001	3	16
BREAST	Putrescine biosynthetic process →	-0.228	-0.962	<.001	<.001	3	12
PANCREAS	Putrescine metabolic process →	-0.159	-1.324	.001	<.001	3	10
LIVER	Primary amino compound biosynthetic process →	+1.447	+3.350	<.001	<.001	3	7
BLOOD_Myeloma	Regulation of DNA stability →	+0.151	+2.361	<.001	<.001	3	7
LIVER	Ribonucleoside diphosphate biosynthetic process →	+0.143	+3.525	.002	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,687 associations by consensus.

Putrescine biosynthetic process from arginine by AGMAT expression — BREAST

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