AGL

Across TCGA patient cohorts, AGL RNA expression is significantly associated with the protein abundance of many other proteins, with 11,251 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AGL-associated proteins across cancer lineages are PPIB, RIN3, and SEC24A. Each is linked with AGL in more than 3 cancer types. Because this analysis shows association rather than direction, both AGL-to-partner and partner-to-AGL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AGL versus PPIB in GBM, with a Pearson correlation of -0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AGL→partner) and Y-score (partner→AGL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PPIB →	-0.471	-0.710	<.001	<.001	3	4
GBM	RIN3 →	-0.345	-0.371	<.001	.003	3	4
HNSC	SEC24A →	-0.295	-0.568	<.001	<.001	3	4
HNSC	HDLBP →	-0.249	-0.657	<.001	<.001	3	4
HNSC	HSPA13 →	-0.428	-0.538	<.001	.001	3	4
LSCC	PLEKHO2 →	-0.282	-0.629	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,251 associations by consensus.

AGL vs PPIB — GBM

Explore this scatter interactively →