AGL

Across TCGA patient cohorts, AGL protein abundance is significantly associated with the RNA expression of many other genes, with 10,250 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible AGL-associated genes across cancer lineages are DBT, FAM189A2, and ZMYND12. Each is linked with AGL in more than 5 cancer types. Because this analysis shows association rather than direction, both AGL-to-partner and partner-to-AGL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AGL versus DBT in LSCC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGL→partner) and Y-score (partner→AGL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DBT →	+0.419	+0.306	<.001	<.001	3	6
UCEC	FAM189A2 →	+1.676	+0.303	<.001	<.001	3	5
LUAD	ZMYND12 →	+0.715	+0.356	<.001	<.001	3	5
BRCA	ERBB4 →	+1.557	+0.478	<.001	<.001	3	5
BRCA	HJURP →	-0.975	-0.471	<.001	<.001	3	5
UCEC	C16orf89 →	+1.495	+0.184	.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,250 associations by consensus.

AGL vs DBT — LSCC

Explore this scatter interactively →