AGGF1

Across TCGA cell cohorts, AGGF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,070 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AGGF1-associated GO terms across cancer lineages are Nucleotide-excision repair, DNA damage tolerance, and Translesion synthesis. Each is linked with AGGF1 in more than 14 cancer types. Because this analysis shows association rather than direction, both AGGF1-to-partner and partner-to-AGGF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleotide-excision repair grouped by AGGF1-low versus AGGF1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AGGF1→partner) and Y-score (partner→AGGF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Nucleotide-excision repair →	+0.076	+0.793	.008	.002	2	15
SKIN	DNA damage tolerance →	+0.092	+0.531	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Translesion synthesis →	+0.070	+0.696	<.001	<.001	3	13
LARGE_INTESTINE	Centrosome cycle →	+0.084	+0.655	<.001	<.001	3	13
BLOOD_Myeloma	Positive regulation of organelle assembly →	+0.062	+0.657	<.001	.002	3	12
SKIN	Double-strand break repair via nonhomologous end joining →	+0.053	+0.538	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,070 associations by consensus.

Nucleotide-excision repair by AGGF1 expression — OESOPHAGUS

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