AGFG2

Across TCGA patient cohorts, AGFG2 mutation is significantly associated with the RNA expression of many other genes, with 1,021 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AGFG2-associated genes across cancer lineages are TRMT112P1, LINC00458, and LINC02559. Each is linked with AGFG2 in more than 2 cancer types. Because this analysis shows association rather than direction, both AGFG2-to-partner and partner-to-AGFG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRMT112P1 grouped by AGFG2-low versus AGFG2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGFG2→partner) and Y-score (partner→AGFG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TRMT112P1 →	+0.036	+2.993	.006	.008	3	3
CESC	LINC00458 →	+0.385	+3.653	<.001	.009	3	2
CESC	LINC02559 →	+1.058	+4.757	<.001	.004	3	2
CESC	MIR4478 →	+1.169	+3.996	<.001	.005	3	2
UCEC	CHAF1A →	+0.449	+1.684	.007	.007	3	2
UCEC	STIP1 →	+0.471	+2.724	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,021 associations by consensus.

TRMT112P1 by AGFG2 expression — SKCM

Explore this box plot interactively →