AGFG2

Across TCGA cell cohorts, AGFG2 mutation is significantly associated with the RNA expression of many other genes, with 192 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AGFG2-associated genes across cancer lineages are PROP1, KRTAP2-4, and DPEP2NB. Each is linked with AGFG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both AGFG2-to-partner and partner-to-AGFG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PROP1 grouped by AGFG2-low versus AGFG2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGFG2→partner) and Y-score (partner→AGFG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PROP1 →	+0.022	+2.639	<.001	.002	3	2
SOFT_TISSUE	KRTAP2-4 →	+0.122	+4.930	<.001	.008	3	1
SOFT_TISSUE	DPEP2NB →	+0.025	+4.930	<.001	.008	3	1
LARGE_INTESTINE	CBY1 →	+0.796	+3.330	<.001	.002	3	1
LARGE_INTESTINE	CTSZ →	-1.179	-3.169	.001	.009	3	1
LARGE_INTESTINE	IL7 →	+0.809	+3.299	.006	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 192 associations by consensus.

PROP1 by AGFG2 expression — LARGE_INTESTINE

Explore this box plot interactively →