Across TCGA patient cohorts, AGER protein abundance is significantly associated with the protein abundance of many other proteins, with 7,456 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AGER-associated proteins across cancer lineages are ARHGAP24_S391, ACP5, and ACTA1. Each is linked with AGER in more than 2 cancer types. Because this analysis shows association rather than direction, both AGER-to-partner and partner-to-AGER results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AGER→partner) and Y-score (partner→AGER) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARHGAP24_S391 →	+0.466	+0.489	<.001	<.001	3	3
LSCC	ACP5 →	+0.375	+0.323	<.001	<.001	3	2
LSCC	ACTA1 →	+0.222	+0.316	<.001	.002	3	2
LUAD	ACTN2 →	+0.368	+0.307	<.001	<.001	3	2
LUAD	ACVRL1_S161 →	+0.723	+0.414	<.001	<.001	3	2
LSCC	ADAMTS1 →	+0.393	+0.462	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,456 associations by consensus.

Exploration

AGER survival (RNA) · tumor vs normal (RNA) · all AGER data types