Across TCGA cell cohorts, AGER RNA expression is significantly associated with the go_rna of many other GO terms, with 4,128 significant associations in total. BONE shows the largest number of these associations.

The most reproducible AGER-associated GO terms across cancer lineages are Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway, Positive regulation of dendritic cell differentiation, and Negative regulation of myoblast fusion. Each is linked with AGER in more than 14 cancer types. Because this analysis shows association rather than direction, both AGER-to-partner and partner-to-AGER results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AGER→partner) and Y-score (partner→AGER) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.135	+1.232	<.001	<.001	3	14
LIVER	Positive regulation of dendritic cell differentiation →	-0.196	-1.035	.003	.004	2	15
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.157	+1.143	.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Taurine biosynthetic process →	+1.265	+1.281	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Alkanesulfonate biosynthetic process →	+1.265	+1.281	<.001	<.001	3	14
BONE	Regulation of monoatomic ion transmembrane transport →	-0.066	-0.995	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,128 associations by consensus.

Exploration

AGER survival (RNA) · tumor vs normal (RNA) · all AGER data types