AGBL5

Across TCGA patient cohorts, AGBL5 mutation is significantly associated with the RNA expression of many other genes, with 4,908 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AGBL5-associated genes across cancer lineages are DUS3L, LINC01335, and RNA5SP369. Each is linked with AGBL5 in more than 2 cancer types. Because this analysis shows association rather than direction, both AGBL5-to-partner and partner-to-AGBL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DUS3L grouped by AGBL5-low versus AGBL5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGBL5→partner) and Y-score (partner→AGBL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DUS3L →	+0.360	+2.567	.001	<.001	3	3
LGG	LINC01335 →	+0.590	+5.206	<.001	.007	3	3
CESC	RNA5SP369 →	+0.170	+3.539	.003	.003	3	3
UCEC	RPS29P32 →	+0.219	+1.599	.004	.007	3	3
ESCA	RNA5SP141 →	+1.550	+3.599	<.001	.008	3	3
ESCA	RNA5SP56 →	+0.291	+3.759	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,908 associations by consensus.

DUS3L by AGBL5 expression — UCEC

Explore this box plot interactively →