AGBL5

Across TCGA cell cohorts, AGBL5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,217 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AGBL5-associated GO terms across cancer lineages are Microtubule cytoskeleton organization involved in mitosis, Positive regulation of intracellular steroid hormone receptor signaling pathway, and Regulation of double-strand break repair. Each is linked with AGBL5 in more than 13 cancer types. Because this analysis shows association rather than direction, both AGBL5-to-partner and partner-to-AGBL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule cytoskeleton organization involved in mitosis grouped by AGBL5-low versus AGBL5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AGBL5→partner) and Y-score (partner→AGBL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Microtubule cytoskeleton organization involved in mitosis →	+0.129	+1.069	.004	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.182	+1.239	<.001	<.001	3	14
BONE	Regulation of double-strand break repair →	+0.063	+0.840	<.001	<.001	3	14
BONE	Establishment of mitotic spindle localization →	+0.113	+0.911	.002	<.001	3	13
BONE	Establishment of spindle orientation →	+0.128	+0.993	.001	.002	3	13
SOFT_TISSUE	Positive regulation of cell division →	+0.135	+0.873	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,217 associations by consensus.

Microtubule cytoskeleton organization involved in mitosis by AGBL5 expression — BONE

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