AGBL5

Across TCGA cell cohorts, AGBL5 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AGBL5-associated genes across cancer lineages are ASB11, OR56A1, and OR52L1. Each is linked with AGBL5 in more than 1 cancer types. Because this analysis shows association rather than direction, both AGBL5-to-partner and partner-to-AGBL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASB11 grouped by AGBL5-low versus AGBL5-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGBL5→partner) and Y-score (partner→AGBL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ASB11 →	+0.052	+4.350	<.001	.005	3	1
BLOOD_Lymphoma	OR56A1 →	+0.038	+4.523	<.001	.004	3	1
BLOOD_Lymphoma	OR52L1 →	+0.063	+4.191	<.001	.007	3	1
SOFT_TISSUE	DPPA4 →	+1.395	+3.678	<.001	.009	3	1
SOFT_TISSUE	SYNPR →	+0.485	+3.736	<.001	.008	3	1
SOFT_TISSUE	MRGPRX2 →	+0.057	+4.169	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

ASB11 by AGBL5 expression — BLOOD_Lymphoma

Explore this box plot interactively →