AGBL5-AS1

Across TCGA pan-cancer cohorts, AGBL5-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of AGBL5-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where AGBL5-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types AGBL5-AS1 is over-expressed in tumor, although a few such as BLCA and READ show the opposite, repressed pattern.

BLCA, READ, and BRCA are the cancer types where AGBL5-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in AGBL5-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	III,IV	−0.681	.030	6	view →
READ	All	II,III,IV	−0.542	.007	6	view →
BRCA	Female	II,III,IV	−0.153	.001	6	view →
KIRP	Female	All	+0.354	.024	5	view →
HNSC	All	All	+0.138	.015	5	view →
COAD	All	All	−0.190	<.001	4	view →
LIHC	Male	All	+0.193	.006	3	view →
KIRC	Female	All	+0.169	.006	3	view →
UCEC	All	III,IV	−0.488	.046	2	view →
ESCA	All	II,III,IV	+0.360	.026	2	view →
PAAD	All	All	+0.114	.027	2	view →
CHOL	Female	All	+0.523	.030	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

AGBL5-AS1–BLCA

Open the BLCA breakdown →