Across TCGA cell cohorts, AGBL4 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible AGBL4-associated genes across cancer lineages are C1orf189, SSX5, and OR4D6. Each is linked with AGBL4 in more than 1 cancer types. Because this analysis shows association rather than direction, both AGBL4-to-partner and partner-to-AGBL4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGBL4→partner) and Y-score (partner→AGBL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	C1orf189 →	+0.218	+3.865	<.001	.006	3	1
SOFT_TISSUE	SSX5 →	+0.149	+3.635	<.001	.007	3	1
SOFT_TISSUE	OR4D6 →	+0.028	+4.392	<.001	.004	3	1
SOFT_TISSUE	KLRF2 →	+0.014	+4.392	<.001	.004	3	1
SOFT_TISSUE	MYH4 →	+0.023	+4.139	.009	.007	3	1
OESOPHAGUS	TAS2R39 →	+0.043	+4.906	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

AGBL4 survival (RNA) · tumor vs normal (RNA) · all AGBL4 data types