AGBL3

Across TCGA cell cohorts, AGBL3 mutation is significantly associated with the RNA expression of many other genes, with 155 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AGBL3-associated genes across cancer lineages are CST9L, IFNA8, and IL25. Each is linked with AGBL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both AGBL3-to-partner and partner-to-AGBL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CST9L grouped by AGBL3-low versus AGBL3-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGBL3→partner) and Y-score (partner→AGBL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CST9L →	+0.028	+5.369	<.001	.004	3	1
SOFT_TISSUE	IFNA8 →	+0.034	+4.930	<.001	.008	3	1
SOFT_TISSUE	IL25 →	+0.020	+5.977	<.001	.001	3	1
SOFT_TISSUE	RLN3 →	+0.059	+5.369	<.001	.004	3	1
SOFT_TISSUE	SCGB1C1 →	+0.073	+5.977	<.001	.001	3	1
SOFT_TISSUE	MROH5 →	+0.021	+4.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 155 associations by consensus.

CST9L by AGBL3 expression — SOFT_TISSUE

Explore this box plot interactively →