AGBL1-AS1

Across TCGA pan-cancer cohorts, AGBL1-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated AGBL1-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher AGBL1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated AGBL1-AS1 expression acts as an unfavorable survival marker, although some lineages such as MESO and ESCA show a favorable association.

KIRC, KICH, and UVM are the cancer types where AGBL1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Quartile	All	0.461	0.662	<.001	121	view →
KICH	OS	Tertile	III,IV	0.162	0.763	<.001	78	view →
UVM	DFS	Tertile	All	0.392	0.682	.003	57	view →
MESO	DFS	Tertile	II,III,IV	0.487	0.211	.006	54	view →
ESCA	DFS	Quartile	All	0.870	0.174	.004	48	view →
ACC	OS	Tertile	All	0.174	0.751	<.001	48	view →
READ	DFS	Tertile	All	0.207	0.598	.003	36	view →
CHOL	OS	Tertile	All	0.089	0.727	.001	27	view →
LUSC	OS	Quartile	All	0.672	0.781	.002	24	view →
LIHC	DFS	Tertile	All	0.308	0.566	.008	24	view →
HNSC	OS	Median	All	0.718	0.816	.006	21	view →
SKCM	DFS	Median	All	0.687	0.576	.004	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

AGBL1-AS1–KIRC (OS)

Open the KIRC breakdown →