Across TCGA patient cohorts, AGAP9 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AGAP9-associated genes across cancer lineages are FoxM1, EGFR_pY1068, and eIF4G. Each is linked with AGAP9 in more than 1 cancer types. Because this analysis shows association rather than direction, both AGAP9-to-partner and partner-to-AGAP9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGAP9→partner) and Y-score (partner→AGAP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.244	+1.906	.019	.016	3	2
UCEC	EGFR_pY1068 →	-0.274	-2.415	.006	.003	3	1
UCEC	eIF4G →	+0.279	+2.999	.025	.035	3	1
UCEC	ERK2 →	+0.207	+2.000	.007	.030	3	1
UCEC	JNK_pT183_Y185 →	-0.215	-1.893	.001	.016	3	1
UCEC	JNK2 →	+0.270	+3.710	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Exploration

AGAP9 survival (RNA) · tumor vs normal (RNA) · all AGAP9 data types