AGAP7P

Across TCGA patient cohorts, AGAP7P mutation is significantly associated with the RNA expression of many other genes, with 2,174 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AGAP7P-associated genes across cancer lineages are RNA5SP249, MIR4662B, and TAF9. Each is linked with AGAP7P in more than 1 cancer types. Because this analysis shows association rather than direction, both AGAP7P-to-partner and partner-to-AGAP7P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP249 grouped by AGAP7P-low versus AGAP7P-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGAP7P→partner) and Y-score (partner→AGAP7P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNA5SP249 →	+0.294	+9.057	<.001	.003	3	2
UCEC	MIR4662B →	+0.189	+3.484	<.001	<.001	3	2
UCEC	TAF9 →	+0.558	+2.392	<.001	<.001	3	2
UCEC	CASTOR2 →	+0.649	+1.695	.001	.007	3	2
UCEC	MYO19 →	+0.456	+2.392	.001	<.001	3	2
BLCA	MRPL51P2 →	+0.114	+7.640	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,174 associations by consensus.

RNA5SP249 by AGAP7P expression — BRCA

Explore this box plot interactively →