Across TCGA cell cohorts, AGAP6 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AGAP6-associated genes across cancer lineages are CRYBB1, OR2V1, and SERPINA10. Each is linked with AGAP6 in more than 1 cancer types. Because this analysis shows association rather than direction, both AGAP6-to-partner and partner-to-AGAP6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGAP6→partner) and Y-score (partner→AGAP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	CRYBB1 →	+0.026	+4.906	<.001	.006	3	1
LARGE_INTESTINE	OR2V1 →	+0.042	+4.095	.004	.009	3	1
BLOOD_Leukemia	SERPINA10 →	+0.133	+3.912	<.001	.006	3	1
BLOOD_Leukemia	GOLGA6C →	+0.061	+3.934	<.001	.005	3	1
BLOOD_Leukemia	SYNDIG1L →	+0.062	+3.978	<.001	.005	3	1
BLOOD_Leukemia	LRRC55 →	+0.005	+4.507	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

AGAP6 survival (RNA) · tumor vs normal (RNA) · all AGAP6 data types