AGAP3

Across TCGA patient cohorts, AGAP3 protein abundance is significantly associated with the RNA expression of many other genes, with 6,539 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AGAP3-associated genes across cancer lineages are ZEB2, LINC00957, and C1QB. Each is linked with AGAP3 in more than 3 cancer types. Because this analysis shows association rather than direction, both AGAP3-to-partner and partner-to-AGAP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AGAP3 versus ZEB2 in HNSC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGAP3→partner) and Y-score (partner→AGAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZEB2 →	+0.627	+0.204	<.001	.001	3	4
GBM	LINC00957 →	+0.697	+0.315	<.001	<.001	3	4
LUAD	C1QB →	+0.637	+0.186	.004	<.001	3	3
LSCC	C1QA →	+0.822	+0.215	.001	.002	3	3
PDAC	ACSM5 →	+0.372	+0.158	<.001	.001	3	3
COAD	MSR1 →	+0.773	+0.213	.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,539 associations by consensus.

AGAP3 vs ZEB2 — HNSC

Explore this scatter interactively →