AGAP3

Across TCGA cell cohorts, AGAP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,783 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible AGAP3-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Negative regulation of translational initiation, and Regulation of telomeric loop disassembly. Each is linked with AGAP3 in more than 13 cancer types. Because this analysis shows association rather than direction, both AGAP3-to-partner and partner-to-AGAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by AGAP3-low versus AGAP3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AGAP3→partner) and Y-score (partner→AGAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.215	+1.222	<.001	<.001	3	14
BONE	Negative regulation of translational initiation →	+0.130	+1.158	<.001	<.001	3	12
BONE	Regulation of telomeric loop disassembly →	+0.132	+1.261	.001	<.001	3	11
BONE	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.157	+0.888	<.001	<.001	3	11
SKIN	Positive regulation of neuron migration →	+0.100	+1.245	<.001	<.001	3	11
BONE	Negative regulation of mRNA splicing, via spliceosome →	+0.109	+1.288	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,783 associations by consensus.

Pre-mRNA catabolic process by AGAP3 expression — BONE

Explore this box plot interactively →