AGAP14P

Across TCGA patient cohorts, AGAP14P mutation is significantly associated with the RNA expression of many other genes, with 568 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AGAP14P-associated genes across cancer lineages are CMC4, RNA5SP97, and RPA3P2. Each is linked with AGAP14P in more than 1 cancer types. Because this analysis shows association rather than direction, both AGAP14P-to-partner and partner-to-AGAP14P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CMC4 grouped by AGAP14P-low versus AGAP14P-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AGAP14P→partner) and Y-score (partner→AGAP14P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CMC4 →	+0.053	+5.080	.002	.008	3	2
SKCM	RNA5SP97 →	+0.381	+3.186	<.001	.009	3	2
SKCM	RPA3P2 →	+0.140	+3.669	<.001	.001	3	2
SKCM	RPS26P54 →	+0.306	+3.777	<.001	.002	3	2
LGG	RNU6-1222P →	+0.423	+7.977	<.001	.007	3	2
UCEC	ILKAP →	+0.411	+3.499	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 568 associations by consensus.

CMC4 by AGAP14P expression — COAD

Explore this box plot interactively →