AGA

Across TCGA patient cohorts, AGA RNA expression is significantly associated with the protein abundance of many other proteins, with 7,417 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible AGA-associated proteins across cancer lineages are ARFIP1, CDC42BPB, and MLPH. Each is linked with AGA in more than 4 cancer types. Because this analysis shows association rather than direction, both AGA-to-partner and partner-to-AGA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AGA versus ARFIP1 in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AGA→partner) and Y-score (partner→AGA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ARFIP1 →	+0.341	+0.724	.001	.002	3	5
BRCA	CDC42BPB →	+0.220	+0.453	<.001	<.001	3	4
BRCA	MLPH →	+0.599	+0.448	<.001	<.001	3	3
GBM	NCAPG_S674 →	-0.707	-0.406	<.001	.009	3	3
BRCA	NCAPH →	-0.653	-0.551	<.001	<.001	3	3
BRCA	NGDN_S143 →	-0.511	-0.675	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,417 associations by consensus.

AGA vs ARFIP1 — OV

Explore this scatter interactively →