AFTPH

Across TCGA patient cohorts, AFTPH RNA expression is significantly associated with the protein abundance of many other proteins, with 16,336 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AFTPH-associated proteins across cancer lineages are HEATR5B, SYNRG, and MDH1. Each is linked with AFTPH in more than 6 cancer types. Because this analysis shows association rather than direction, both AFTPH-to-partner and partner-to-AFTPH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AFTPH versus HEATR5B in OV, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AFTPH→partner) and Y-score (partner→AFTPH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HEATR5B →	+0.233	+0.552	<.001	<.001	3	7
CCRCC	SYNRG →	+0.252	+0.394	<.001	<.001	3	6
OV	MDH1 →	+0.335	+0.413	<.001	.002	3	5
BRCA	SPR →	+0.524	+0.566	<.001	<.001	3	5
BRCA	STK17B →	-0.457	-0.504	<.001	.005	3	5
LSCC	ARHGEF6_S225 →	-0.545	-0.439	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,336 associations by consensus.

AFTPH vs HEATR5B — OV

Explore this scatter interactively →