AFTPH

Across TCGA patient cohorts, AFTPH protein abundance is significantly associated with the RNA expression of many other genes, with 10,863 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible AFTPH-associated genes across cancer lineages are TGFB3, PDPN, and DACT1. Each is linked with AFTPH in more than 5 cancer types. Because this analysis shows association rather than direction, both AFTPH-to-partner and partner-to-AFTPH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AFTPH versus TGFB3 in OV, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AFTPH→partner) and Y-score (partner→AFTPH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TGFB3 →	-1.284	-0.339	<.001	<.001	3	6
OV	PDPN →	-0.957	-0.228	.002	<.001	3	6
CCRCC	DACT1 →	-1.114	-0.283	<.001	<.001	3	6
CCRCC	VGLL3 →	-0.942	-0.279	<.001	<.001	3	6
CCRCC	LOXL2 →	-1.329	-0.280	<.001	<.001	3	6
OV	ZEB2 →	-0.627	-0.207	.006	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,863 associations by consensus.

AFTPH vs TGFB3 — OV

Explore this scatter interactively →