Across TCGA patient cohorts, AFMID RNA expression is significantly associated with the protein abundance of many other proteins, with 16,322 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AFMID-associated proteins across cancer lineages are CBX8, DYNLL2, and MSI2. Each is linked with AFMID in more than 5 cancer types. Because this analysis shows association rather than direction, both AFMID-to-partner and partner-to-AFMID results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AFMID→partner) and Y-score (partner→AFMID) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CBX8 →	+0.498	+0.722	<.001	<.001	3	6
BRCA	DYNLL2 →	+0.453	+0.744	.001	.009	3	6
BRCA	MSI2 →	+0.540	+0.891	<.001	<.001	3	5
BRCA	THEMIS2 →	-0.506	-0.992	<.001	<.001	3	5
COAD	BPTF →	+0.261	+0.393	.004	.002	3	5
LSCC	AKAP1 →	+0.422	+0.610	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,322 associations by consensus.

Exploration

AFMID survival (RNA) · tumor vs normal (RNA) · all AFMID data types