Across TCGA cell cohorts, AFMID mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AFMID-associated genes across cancer lineages are PTPRQ and RTL4. Each is linked with AFMID in more than 1 cancer types. Because this analysis shows association rather than direction, both AFMID-to-partner and partner-to-AFMID results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AFMID→partner) and Y-score (partner→AFMID) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PTPRQ →	+0.036	+4.551	.001	.004	3	1
BLOOD_Leukemia	RTL4 →	+0.024	+4.152	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

AFMID survival (RNA) · tumor vs normal (RNA) · all AFMID data types