AFG3L2

Across TCGA patient cohorts, AFG3L2 protein abundance is significantly associated with the protein abundance of many other proteins, with 23,444 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AFG3L2-associated proteins across cancer lineages are SAMM50, SLC25A13, and SLC25A3. Each is linked with AFG3L2 in more than 9 cancer types. Because this analysis shows association rather than direction, both AFG3L2-to-partner and partner-to-AFG3L2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AFG3L2 versus SAMM50 in UCEC, with a Pearson correlation of 0.83.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AFG3L2→partner) and Y-score (partner→AFG3L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SAMM50 →	+0.652	+0.632	<.001	<.001	3	10
UCEC	SLC25A13 →	+0.593	+0.563	<.001	<.001	3	10
UCEC	SLC25A3 →	+0.790	+0.672	<.001	<.001	3	10
OV	SLC25A5 →	+0.661	+0.612	<.001	<.001	3	10
UCEC	ATP5PB →	+0.628	+0.666	<.001	<.001	3	10
UCEC	ATP5PD →	+0.662	+0.574	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,444 associations by consensus.

AFG3L2 vs SAMM50 — UCEC

Explore this scatter interactively →