AFG1L

Across TCGA cell cohorts, AFG1L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,206 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AFG1L-associated GO terms across cancer lineages are 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process, Glutaminyl-tRNAGln biosynthesis via transamidation, and Quinone biosynthetic process. Each is linked with AFG1L in more than 11 cancer types. Because this analysis shows association rather than direction, both AFG1L-to-partner and partner-to-AFG1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process grouped by AFG1L-low versus AFG1L-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AFG1L→partner) and Y-score (partner→AFG1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process →	+0.092	+0.480	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Glutaminyl-tRNAGln biosynthesis via transamidation →	+0.086	+0.687	<.001	<.001	3	11
LARGE_INTESTINE	Quinone biosynthetic process →	+0.094	+0.548	<.001	.003	3	11
LARGE_INTESTINE	Ubiquinone biosynthetic process →	+0.094	+0.548	<.001	.003	3	11
LARGE_INTESTINE	Ubiquinone metabolic process →	+0.093	+0.603	<.001	<.001	3	9
BREAST	Regulation of mitochondrial gene expression →	+0.071	+0.503	.004	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,206 associations by consensus.

1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process by AFG1L expression — SKIN

Explore this box plot interactively →